Wolfhard Frost · Bessemerweg 13 · 33611 Bielefeld
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PSA Selbsthilfegruppe Prostatakrebs Bielefeld

mpMRT vor einer Biopsie

09.3.2018

mpMRT vor einer Biopsie

 

mpMRT verbessert lt. einer australischen Studie die diagnostische Genauigkeit und sollte als Instrument vor der Biopsie für bessere Biopsieergebnisse eingesetzt zu werden. Die Vorhersage(prädiktive)-Genauigkeit für signifikantes Prostatakarzinom (PCa) sei bei 9 %, schreibt das Univadis-Medizinportal.

Quelle:
BJU Int. 2017 Dec;120(6):774-781. doi: 10.1111/bju.13814. Epub 2017 Mar 31.
A multiparametric magnetic resonance imaging-based risk model to determine the risk of significant prostate cancer prior to biopsy.

 

Quelle:
NMR Biomed. 2016 Mar;29(3):232-8. doi: 10.1002/nbm.3452. Epub 2016 Jan 5.
Stratification of the aggressiveness of prostate cancer using pre-biopsy multiparametric MRI (mpMRI)
„…
One hundred and twenty men suspected to have prostate cancer underwent mpMRI (diffusion MRI and MR spectroscopic imaging) prior to biopsy. Twenty-six had cancer and were stratified into three groups based on GS: low grade (GS ≤ 6), intermediate grade (GS = 7) and high grade (GS ≥ 8)….These data indicate that pre-biopsy mpMRI may stratify PCa aggressiveness noninvasively. As the recent literature data suggest that men with GS ≤ 6 cancer may not need radical therapy, our data may help limit the need for biopsy and allow informed decision making for clinical intervention.“
Author information: Department of NMR & MRI Facility, All India Institute of Medical Sciences, New Delhi, India./ Department of Urology, All India Institute of Medical Sciences, New Delhi, India./ Department of Radio-diagnosis, All India Institute of Medical Sciences, New Delhi, India./ Department of Pathology, All India Institute of Medical Sciences, New Delhi, India.

 

Prostatakrebs: Risikostratifizierung bei PCPTRC-Schätzungen von < 10 % mit MRT besser

 

Magnetic Resonance Imaging Provides Added Value to the Prostate Cancer Prevention Trial Risk Calculator for Patients With Estimated Risk of High-grade Prostate Cancer Less Than or Equal to 10%
DOI: 
https://doi.org/10.1016/j.urology.2016.08.074
„ ….The use of prostate MRI in addition to the Prostate Cancer Prevention Trial risk calculator provides a significant improvement in clinical risk discrimination for patients with estimated risk of high-grade (Gleason ≥7) prostate cancer ≤10%. Prebiopsy prostate MRI should be strongly considered for these patients.“

Prostatakarzinom neues Vorhersage-Nomogramm

Quelle: BJU Int. 2017 Jul;120(1):76-82. doi: 10.1111/bju.13733. Epub 2017 Jan 6. Development and external validation of a biopsy-derived nomogram to predict risk of ipsilateral extraprostatic extension.
„…The nomogram predicting risk of EPE had a predictive accuracy of 0.74 in the external validation cohort“

09.03.2018 verkürzt und laiensprachlich aufbereitet für die PSA Selbsthilfegruppe Prostatakrebs Bielefeld e.V. durch WDF

 



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